韩进松
发布人:工学院1  发布时间:2019-04-08   浏览次数:6451


韩进松博士 (Prof. Dr. Jinsong Han)

中国药科大学工学院,教授,博士生导师

  

联系方式:

Email: jinsong.han@cpu.edu.cn

中国江苏省南京市江宁区,龙眠大道639号,实训楼516邮政编码: 211198

课题组主页:http://www.jinsonglab.com/

  

课题组研究主要集中在运用机器学习、组合化学、计算化学等策略快速设计、合成、构建便携式荧光阵列传感器,并应用于生物医学等领域例如临床疾病诊断,食品和药品质量控制。同时,应用计算机辅助药物设计、高通量筛选等技术制备及合成小分子药物应用于治疗癌症等疾病近三年在Chem (CellPress), Nature Biotechnology, Angew. Chem. Int. Ed., PNAS等国际权威期刊上发表论文20余篇,工作受到包括英国广播公司BBC, 科学杂志社SCIENCE, 细胞杂志社CELL新华社和科学网等超过100多家国内外知名媒体及杂志社的专访和新闻报道入选江苏省双创人才等。

  

研究方向 (Research Interest)

(1) 食品药品质量控制及疾病的快速检测设计合成及构建新型荧光阵列传感器并应用于分析检测

(2) 药物化学与药物合成:机器学习及计算机辅助药物设计,药物合成及生物活性评估

  

本课题组热忱欢迎本科生、硕士生、博士研究生、博士后以及科研助理人员的加入

You are welcome to join our Lab as graduates or postdoc

欢迎申请:https://www.jinsonglab.com/vacancies

  

学习与工作经历 (Experience)

2019-至今,中国药科大学工学院,教授,博导,课题组长。

2017-2019[瑞典] Karolinska Institutet, Bioengineering,博士后(Supervisor: Prof. Linxian Li

2014-2017[德国] Universit?t Heidelberg, Chemistry,博士学位(Supervisor: Prof. Uwe Bunz

2010-2013,第二军医大学,药物化学,医学硕士学位(Supervisor: Prof. 朱驹 /宋云龙

2006-2010,中国药科大学,中药学,学士学位

  

部分代表作(Publication, 2016-2019):

16) F. Li#, Jinsong Han# (Equal contribution), T. Cao, W. Lam, B. Fan, W. Tang, S. Chen, Kin Lam Fok* and L. Li*: Design of self-assembly dipeptide hydrogels and machine learning via their chemical features. PNAS,2019, 116(23), 11259-11264.

Highlighted in “MIT Technology Review”. 

15) B. Wang, Jinsong Han, H. Zhang, A. Biella, M. Bender, K. Seehafer, U. H. F. Bunz*: Detecting Counterfeit Brandies. Chem. Eur. J. 2018, 24, 17361-17366.

14) B. Wang, Jinsong Han, N. M. Bojanowski, M. Bender, C. Ma, K. Seehafer, A. Herrmann, U. H. F. Bunz*: An Optimized Sensor Array Identifies All Natural Amino Acids. ACS Sens. 2018, 3, 1562-1568.

Selected as “Cover” by editors

13) B. Wang#, Jinsong Han# (Equal contribution), M. Bender, S. Hahn, K. Seehafer, Uwe Bunz*: Poly(para-phenyleneethynylene)-Sensor Arrays Discriminate 22 Different Teas. ACS Sens. 2018, 3, 504–511.

12) Jinsong Han, H. Cheng, B. Wang, M. S. Braun, X. Fan, M. Bender, W. Huang, C. Domhan, W. Mier, T. Lindner, K. Seehafer, M. Wink, U. H. F. Bunz: Polymer/Peptide Complex-Based Sensor Array Discriminates Bacteria in Urine. Angew. Chem. Int. Ed. 2017, 56, 15246-15251.

Highlighted as a “Hot Paper”

10) B. Wang#, Jinsong Han# (Equal contribution), C. Ma, M. Bender, K. Seehafer, A. Herrmann, U. H. F. Bunz: A Simple Optoelectronic Tongue Discriminates Amino Acids. Chem. Eur. J. 2017, 23, 12471-12474.

Highlighted as a “Hot Paper” by the editors

9) Jinsong Han, C. Ma, B. Wang, M. Bender, M. Bojanowski, M. Hergert, K. Seehafer, A. Herrmann, U. H.F. Bunz: A Hypothesis-Free Sensor Array Discriminates Whiskies for Brand, Age, and Taste. Chem (Cell Press). 2017, 2, 817-824.

Highlighted in over 100 Newspapers, Journals, Radio and TV programs (部分选取的媒体新闻报导):Science News | AAASEurekAlert | AAAS, Chemical & Engineering News 2017,96(24) p9, BBC (Interview)Cell (Interview)Deutschlandfunk (Interview), CAMPUS TV (TV Interview), ScienceNewslinePopular ScienceHeidelberg University Press ReleasePhys.org, Daily RecordXINHUANET (新华网), CGTN (中国国际电视台), News.cn(新华社), Sciencenet(科学网新闻), X-MOL(新闻), THE PAPER(澎湃新闻), Sina(新浪新闻), Sohu(搜狐新闻), etc.

8) B. Wang#, Jinsong Han# (Equal contribution), M. Bender, K. Seehafer, U. H. F. Bunz: Array-Based Sensing of Explosives by Water-Soluble Poly(pphenyleneethynylene)s. Macromolecules 2017, 50, 4126-4131.

7) Jinsong Han, B. Wang, M. Bender, J. Pfisterer, W. Huang, K. Seehafer, M. Yazdani, V. M. Rotello, C. M. Rotello, U. H. F. Bunz: Fingerprinting antibiotics with PAE-based fluorescent sensor arrays. Polymer Chemistry 2017, 8, 2723-2732.

6) Jinsong Han, B. Wang, M. Bender, K. Seehafer, U. H. F. Bunz: Poly(p-phenyleneethynylene)-based tongues discriminate fruit juices. Analyst 2017, 142, 537-543.

Highlighted in ChemistryWorld (RSC)

5) Jinsong Han, B. Wang, M. Bender, S. Kushida, K. Seehafer, U. H. F. Bunz: Poly(aryleneethynylene) Tongue Identifies Nonsteroidal Anti-inflammatory Drugs in Water: A Test Case for Combating Counterfeit Drugs. ACS Appl. Mater. Interfaces 2017, 9, 790–797.

4) Jinsong Han, B. Wang, M. Bender, K. Seehafer, U. H. F. Bunz: Water-Soluble Poly(p-aryleneethynylene)s: A Sensor Array Discriminates Aromatic Carboxylic Acids. ACS Appl. Mater. Interfaces 2016, 8, 20415–20421.

3) Jinsong Han, M. Bender, K. Seehafer, U. H. F. Bunz: Identification of White Wines by using Two Oppositely Charged Poly(p-phenyleneethynylene)s Individually and in Complex. Angew. Chem. Int. Ed. 2016, 55, 7689-7692.

Highlighted in Angew. Chem. Int. Ed. Press Release, Chemical & Engineering News 2016, 94(26), 9Analytik-NewsChemistryViewsX-MOLPHYSORG newschemie.deYumdaEATONWijnWijs.euIDWanalytica-world.comq-more.chemie.deSpektrum.deLABORWELT, Pro-Physik.deinnovations-report, etc.

2) Jinsong Han, M. Bender, S. Hahn, K. Seehafer, U. H. F. Bunz: Polyelectrolyte Complexes Formed from Conjugated Polymers: Array-Based Sensing of Organic Acids. Chem. Eur. J. 2016, 22, 3230-3233.

1) Jinsong Han, Y. Chen, C. Yang, T. Liu, M. Wang, H. Xu, L. Zhang, C. Zheng, Y. Song, J. Zhu*: Structure-based Optimization Leads to the Discovery of NSC765844, A Highly Potent, Less Toxic and Orally Efficacious dual PI3K/mTOR Inhibitor.European Journal of Medicinal Chemistry. 2016, 24, 957-966.

专利Patents):

1) Uwe.H.F. Bunz, Kai Seehafer, Jinsong Han, Markus Bender. (10% share)

Method for identifying a complex analyte.WO2018/055056 A1

2) Ju Zhu, Yunlong Song, Jinsong Han, Ying Chen, Jiaguo Lv, Youjun Zhou. N-(5-(quinolin-6-yl)pyridin-3-yl) benzsulfamide derivatives, preparation method and therapeutic use thereof.PCT/CN2013/086349; WO2014067473 A1; US20160168118 A1; CN 104918933 A; CN103788071A; EP2915810A1; EP2915810A4. Oct 31, 2013.

3) Ju Zhu, Jingjing Huang, Ying Chen, Jinsong Han, Canhui Zheng, Youjun Zhou, Jiaguo Lv, Chongqing Wang, Hao Zhou, Wei Tian, Nannan Sun.3, 4-dihydroisoquinoline antitumor compounds as well as preparation method and application thereof. CN103396361 (A); CN103396361 (B), Jul 24, 2013.

  











 
365bet亚洲手机版